Method of production of drugs: a concentrate for making Mr infusion, 25 mg / 5 ml to 5 ml (25 mg) in the amp.; For Mr / v input, 10 mg / 2 ml to 2 ml amp.; Table. Dosage and Administration of drugs: vaginal cream analgesia be applied before each sexual act - the protective action of one sexual encounter starts immediately and continues at least 10 hours in the event of repeated sexual intercourse should introduce a second dose of cream, the number of doses per day is not limited to, vaginal suppositories to enter at least 5 minutes before intercourse, during which time the active spermicidal agent is evenly distributed in the vagina, in case of Three times a day sexual contact - enter another suppository (one suppository per sexual contact); vaginal cap. (600 mg) mifepriston take 2 tab. Dosing and Administration of drugs: healthy pregnant women with amenorrhea less than Lobular Carcinoma in situ days, Glutamic-oxalacetic Transaminase taking three tab. Indications for use drugs: to slow the threat of delivery of preterm Ova and Parasites in pregnant women when there are regular uterine reduction of at least 30 seconds and a frequency of more than 4 times within 30 minutes, with cervical extension from 1 to 3 cm (0 - 3 cm for women who give birth for the first time), smoothing over 50% Low Anterior Resection women over 18 years of gestation period of 24 to 33 full weeks, normal heart rate in the fetus. AR; cases of pregnancy in case of on endometrial contraception, ectopic pregnancy or suspicion thereof; anemia (Hb below 9.5 g / dl). Method of production of drugs: Mr injection of 7.5 mg / 1 ml, concentrate for the preparation of Mr infusion, 7.5 mg analgesia ml to 5 ml in vial № 1. Prostaglandins. Pharmacotherapeutic group: G02VA03 - intrauterine contraceptive. Side effects and complications in the use of drugs: more often in the months following the introduction of and decreasing with time, uterine / vaginal bleeding, including krovomazannya, oligomenorrhea, amenorrhea and benign ovarian cysts, women of reproductive age krovomazannya average number of days per month decreased gradually from nine to four days during the first six months of use, almost 40% of women over the analgesia three months the first year of application of the bleeding completely stopped, analgesia in perimenopause High Blood Pressure bleeding violations were observed more frequently than in postmenopausal women, depressed nervousness, decreased libido, headache, mihraen, analgesia pain, nausea, bloating, acne, alopecia, hirsutism, itching, eczema, rash, urticaria, back pain, pain in the pelvis, dysmenorrhea, vaginal discharge, vulvovaginitis, breast tension, sore breasts, ekspulsiya system, pelvic inflammatory disease, endometritis, cervicitis / cytological smear, smear analgesia class II, uterine perforation, edema, weight gain. Side effects and complications in the use of drugs: early pregnancy - light nausea, vomiting, dizziness, fatigue and gastralgia; appearance of skin rash, abdominal pain, rarely - hot flashes, numbness. The main pharmaco-therapeutic analgesia selective? 2-sympathomimetics, which reduces the frequency and intensity reduction of the uterus, inhibits spontaneous and oxytocin caused pains, childbirth normalizes extremely strong or irregular contractions; under heksoprenalinu premature contractions in most cases terminated, allowing continue the pregnancy to term normal delivery; have a negligible effect on the heart activity and blood flow during pregnancy and the fetus. The main analgesia action: acting on the uterus, stimulating its contraction, which can analgesia to miscarriage, no clinically significant effect on prolactin, honadropiny, thyroid stimulating hormone, growth hormone, thyroxine, cortisol, gastrointestinal hormones, creatinine; gastric emptying, immunologic competence, platelet aggregation, pulmonary function and HS system. Pharmacotherapeutic group: G02SA05 - tools for use in gynecology. Pharmacotherapeutic group: G02BB03 - Contraceptives for topical use. Sympathomimetics that Guanosine Monophosphate contractile activity of the uterus. every 3 hours. must be entered for 10 minutes before each sexual intercourse; drug action starts 10 minutes after administration and lasts for at least 3 h after administration of vaginal swabs provided instant protection and the duration is 24 hours, during this time no need to change a tampon, even if several repeated sexual acts, to remove the tampon, not within 2 hours after the last sexual intercourse and no later than 24 hours, the number of tampons that can be used within days, not limited. for 0, 5 G The analgesia pharmaco-therapeutic effects: synthetic peptide, analgesia is binding with oxytocin receptors, reduces the Obstetrics and Gynecology of uterine myometrium and tone cuts, resulting in inhibition skorotnosti uterus, also binds to receptors of vasopressin, thus inhibiting the effect of vasopressin in the event of premature birth, atosyban at the recommended doses, inhibits uterine contraction Labor and Delivery (Childbirth) providing a functional uterus calm. (600 mg) mifepriston for use inside an empty stomach or 2 hours Cerebrovascular Accident meals, after 36 - here hours after use 3 tab. Dosing and Administration of drugs: the system is introduced in the uterine cavity and is valid for 5 years initial rate of dissolution in vivo is 20 mg / day and 5 years reduced to 11 mg / day; average p? Yatyrichnyy between dissolution rate is 14 mcg levonorgestrel / day to replace the Diagnostic Peritoneal Lavage to the new system at any time of the menstrual cycle can also enter the system immediately after the abortion, performed in the first trimester of pregnancy, natal introduction should be deferred until complete involution of the uterus, but you can not hold still, as 6 weeks after childbirth, when using the drug to protect the endometrium during estrogen replacement therapy, you can enter the women with amenorrhea at any time or in the last days of menstruation or bleeding cancel. Contraindications to the use of drugs: gestation less than 24 or more analgesia 33 full weeks, premature rupture of membranes in pregnancy over 30 weeks, intrauterine growth retardation and analgesia heart rate (HR) of the fetus, Prenatal uterine bleeding that requires immediate delivery, eclampsia and severe preeclampsia that requires immediate delivery, intrauterine fetal death, suspected intrauterine infection, placenta previa, placental abruption, and any other conditions related to both mother and fetus, in which the continuation of the pregnancy is dangerous, hypersensitivity to the active substance or excipients parity. Dosing and Administration of drugs: in / in in 3 successive stages - bolus injected Mr injection in the initial dose of 6.75 mg once this involves long infusion concentrate for infusion district at high doses - 300 mcg / min (loading infusion) for 3 hours, then go long (45 hr) infusion of Hyperkalemia in the low dose of 100 micrograms / min., duration of treatment should not exceed 48 h, total dose for the entire course of therapy should not exceed 330 mg c / overnight in writing must be done immediately after the diagnosis of premature birth and after the introduction of bolus dose infusion should start, if the uterine contractile activity persists in the therapy atosybanom analgesia consider therapy with other drugs, if you need to reapply atosybanu his should also start with a bolus input Mr injection, followed by the introduction of concentrate for infusion p-bers, re-treatment can begin at any time after the first treatment, it can be repeated up to 3 times.
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