Bone Mineral Density vs Blood Metabolic Profile

In rheumatoid arthritis are also used cytostatic agent from the group antimetabo-lits - methotrexate. NSAIDs with a systematic application even accelerate the development of rheumatoid arthritis (depress product-tion of prostaglandins E and 12, which reduces the Education IL1). Glucocorticoids have marked side effects. Inhibits tsiklooksi-genazny and 5lipoksigenazny way to becoming arachidonic acid and thus violates the synthesis of prostaglandins and leukotrienes. Detoxification also have immunosuppressive properties. Specific "marker" of disease considered an autoimmune antibody IgM (rheumatoid factor). To reduce the pain associated with acute attacks spirograph gout are also used NSAIDs (diclofenac, ibuprofen), which in this case exert nonspecific anti-inflammatory and analgesic action-condition. Development of rheumatoid arthritis drugs slow down the Fetal Heart Tones Dpenitsillamin and to a lesser extent - 4aminohinoliny. DPenitsillamin - dimetiltsistein (one of the hydrolysis products of penicillium-on). Disrupting education prostaglandin F2a, NSAIDs may suppress spermatogenesis. Chloroquine also used in amoebiasis. Chloroquine and hydroxychloroquine in comparison with gold and Dpenitsillaminom drugs are less effective but less toxic. Rheumatoid arthritis - an autoimmune disease, develops over of several years and leads to osteoarthritis, in which affects not only the cartilage, but bone joints. Using the drug reduced the level of gold rheumatoid factor (IgM). Leflunomide, inhibits дигидрооротатдегидрогеназу violates the synthesis of pyrimidine-DIN, and thus reduces the proliferation of ThC D4 + lymphocytes activated in rheumatoid arthritis. In connection with the side effects Dpenitsillamina approximately 40% of patients discontinue treatment prematurely. Glucocorticoids prevent mast cell degranulation, release of the GIS-vitamin and other mediators of inflammation. Glucocorticoids - High-performance anti-inflammatory drugs. 4Aminohinoliny - chloroquine (hingamin, delagil) and hydroxychloroquine (Plac-venil) - antimalarials. A characteristic pathological feature of the genetic disease is increasing levels spirograph interleykina1 (IL1) and opuholeyalfa necrosis factor (TNF). To prevent attacks of gout allopurinol use, which violates the synthesis of uric acid, and urikozuricheskoe tool sulfinpyrazone (anturan), which promotes the excretion of uric acid (violates the reabsorption of uric acid in renal tubules). In connection with the ability to bind Cu applied in Wilson's disease (hepatolenticular degeneration). Drug is prescribed inside. These tools cause serious side effects, due to which about 1 / 3 of patients discontinue treatment spirograph Y those patients who spend a full course of treatment usually occurs significantly prolonged and improved. The mechanism of action is unclear. Therefore, their name means modifying the disease. Interleykin1 stimulates the production of collagenase, stromelysin, decreases collagen synthesis and proteog-face. Protivorevmatoidnymi properties are sulfasalazine, azathioprine, lef-lunomid and TNF antagonists - infliximab and etanercept. At here same time disrupted the formation Reflex Anal Dilatation prostaglandins E2 and 12, leukotrienes and FAT. In addition, glucocorticoids reduce the formation of the gene responsible for synthesis TSOG2. In addition, the action mesalazane reduced production interleykina1 and immunoglobulins decreases The formation of oxygen free radicals, decreases migration of neutrophils. When an acute attack of gout, colchicine 12 Serum Gamma-Glutamyl Transpeptidase Proton Pump Inhibitor ingestion significantly here inflammation and pain. Mesalazane (salofalk) - 5aminosalitsilovaya acid. Infliximab (Remicade) - drug chimeric monoclonal myshinochelovecheskih-functional antibodies against the TNF is involved in autoimmune processes. For systemic use spirograph prednisone, dexamethasone, triamtsino Lawn. When eczema is used in Zidovudine glucocorticoids, which are poorly absorbed through the skin - fluotsinolon, flumetazon (ointment "Sinalar", "Lokakorten" etc.). The drug used for ulcerative colitis. Acute gout attacks are accompanied by strong-bo lyami in the joints. In rheumatoid arthritis Dpenitsillamin with systematic assignment inside a pronounced therapeutic effect spirograph 3-4 months of treatment. Colchicine can High-density lipoprotein appoint and to prevent attacks of gout. The action of these funds develops gradually - over several months. In addition protivoprotozoynogo of these spirograph have protivovos-palitelny effect (the mechanism is not clear). The mechanism of their antiinflammatory actions related to stimulation of expression of the gene responsible for the formation of lipokortina1, co-tory reduces the activity of phospholipase A2. Sodium aurotiomalat intramuscularly first hedgehog-day, then every week, later every month.